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OT: American Politics

Dr. Presto punching in.

I just learned what ibogaine is today and have decided to read the data on it.

1. It's not a cure
2. It's intriguing enough for further study but every single study I've seen from it is horribly designed, with no controlled efficacy data. All uncontrolled randomized unblinded studies, and I don't think I saw any say 80-90% in 1-2 doses anyway. That was a hallucinated stat. Or maybe misunderstood, 80-90% reduction in withdrawal symptoms. Still wrong and not true and can't be confirmed with that single poorly designed uncontrolled study, but that doesn't = cure.
3. Joe Rogan appears to have been tweeting about this drug for at least 15 years. Long lived obsession of his. He's done his own research longer than me, I'll give him that.
4. Claiming 80-90% cure rate for addiction is a wild ass claim and anything close to that effective would have been obvious and approved long ago.
 
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This is the one controlled study I've found:

"Noribogaine showed a nonstatistically significant trend toward decreased total score in opioid withdrawal ratings, most notably at the 120-mg dose."

This study was also flawed (tiny sample) but far better than the uncontrolled slop that make extraordinary claims. The efficacy percentage, if anything, would be in the single digits or teens at best in all likelihood, but it needs further study. Believing 80-90% is dumb.

Also lol at the "study" Rogan cited

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