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OT: Coronavirus Resources - and other things to not worry about

I've got no issues with it. Treating people in a field with nearly zero research behind it is part of the grift though and one of the reasons he is not a board certified physician. But yes, accruing data and medical breakthroughs will play a big part in the field's future.

Just have to remember that until you get concrete data on something, it's gonna be called pseudoscience whether you agree with it or not. I know you seem to really like this guy and I'm sure he's a nice enough fella (this isn't a knock on him at all) but I am just stating facts about who he is and what he does. Which is fine. He got pushed out of his residency, so what? Most people don't even make it that far. I'd like to think I haven't knocked the person at all and am just sticking to good ol' fashioned facts.
 
Preston said:
I've got no issues with it. Treating people in a field with nearly zero research behind it is part of the grift though and one of the reasons he is not a board certified physician. But yes, accruing data and medical breakthroughs will play a big part in the field's future.

Just have to remember that until you get concrete data on something, it's gonna be called pseudoscience whether you agree with it or not. I know you seem to really like this guy and I'm sure he's a nice enough fella (this isn't a knock on him at all) but I am just stating facts about who he is and what he does. Which is fine. He got pushed out of his residency, so what? Most people don't even make it that far. I'd like to think I haven't knocked the person at all and am just sticking to good ol' fashioned facts.
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You keep saying he got pushed out of Johns Hopkins, but he was there for 5 years and then accepted at NIH for 2 years. I know he's talked about it but I don't remember or care why he made the switch.

There's a shitload of research on nutrition and exercise. In fact there are hundreds of papers coming out every week. Obviously you can't read everything but he's got a team of researchers going through the data. There's also a decent amount of research on centenarians. You can learn a lot through advanced blood tests, continuous glucose monitors, etc. etc. They test for a whole bunch of things, like tiny LDL particles which are heavily linked to heart disease.

Small dense LDL particles - a predictor of coronary artery disease evaluated by invasive and CT-based techniques: a case-control study - PMC

Coronary angiography is the current standard method to evaluate coronary atherosclerosis in patients with suspected angina pectoris, but non-invasive CT scanning of the coronaries are increasingly used for the same purpose. Low-density lipoprotein ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
 
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axlsalinger said:
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You keep saying he got pushed out of Johns Hopkins, but he was there for 5 years and then accepted at NIH for 2 years. I know he's talked about it but I don't remember or care why he made the switch.

There's a shitload of research on nutrition and exercise. In fact there are hundreds of papers coming out every week. Obviously you can't read everything but he's got a team of researchers going through the data. There's also a decent amount of research on centenarians. You can learn a lot through advanced blood tests, continuous glucose monitors, etc. etc. They test for a whole bunch of things, like tiny LDL particles which are heavily linked to heart disease.
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He got pushed out and never completed his residency. I don't know why either. And it's okay. I'm not blaming him or mad at him for not completing it. It's not easy. If he did complete it he would have been board certified and likely practicing in a real field. But he didn't so he's doing his own thing. So what?

But yeah I totally get it. Hell, even physiotherapists treat patients using unproven pseudoscientific methods. Many of them are grifters too. This is an even newer field with almost zero medical breakthroughs or proven treatments, yet he has an entire practice treating patients. Do you see what I mean? I'm not knocking him. He's hustling, he seems like a bright guy and you really seem to love him so I trust that he's really kind too. I'm just trying to stick to facts here. I totally get that you like him a lot and I'm not invalidating the love or anything. He's probably a great podcaster and whatnot.
 
Preston said:
I have to say it is weird that it's the grifters with the biggest platforms, most followers, etc. I would have thought that all of this censorship would have meant that people like Stephen Goldstein, Kristian Andersen, Jesse Bloom, etc. would have more followers than some fraud pseudoscience wellness guru. But nope. The libs suck at censoring!!!
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It is an amazing feat, what with the “Libs” trying to “censor” all these whackos peddling disinformation YET THE DISINFORMATION STILL EXISTS EVERYWHERE.

Censorship v2022?
 
Preston said:
He got pushed out and never completed his residency. I don't know why either. And it's okay. I'm not blaming him or mad at him for not completing it. It's not easy. If he did complete it he would have been board certified and likely practicing in a real field. But he didn't so he's doing his own thing. So what?

But yeah I totally get it. Hell, even physiotherapists treat patients using unproven pseudoscientific methods. Many of them are grifters too. This is an even newer field with almost zero medical breakthroughs or proven treatments, yet he has an entire practice treating patients. Do you see what I mean? I'm not knocking him. He's hustling, he seems like a bright guy and you really seem to love him so I trust that he's really kind too. I'm just trying to stick to facts here. I totally get that you like him a lot and I'm not invalidating the love or anything. He's probably a great podcaster and whatnot.
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I enjoy the passive-aggressive insults, it's really productive Preston.

I do know he quit at one place or the other due to burnout because of the long hours along with several other reasons. Who gives a fuck? He was a surgeon who decided it wasn't fulfilling and moved on to other things.

I don't love him, I just think your argument is absurd and feel obliged to reply since I know something about his content (unlike yourself). I do realize it's a complete waste of my time discussing this with you, because you saw a tweet you didn't like and therefore nothing he said in the past or ever says in the future is relevant. But as M.E. once said, maybe somebody else is interested in hearing more.

I can see you will only consider covid takes from medical people if you agree with the content. There's nothing wrong with this type of bias, in fact everybody is biased in some way so it's all good. Just tell me what I want to hear!!
 
Whew, that’s a lotta posts to catch up on. Tweet was pretty idiotic, IMO, and the guy is someone that from what I’ve seen I personally wouldn’t rely on for covid takes, that’s all.
 
axlsalinger said:
I enjoy the passive-aggressive insults, it's really productive Preston.

I do know he quit at one place or the other due to burnout because of the long hours along with several other reasons. Who gives a fuck? He was a surgeon who decided it wasn't fulfilling and moved on to other things.

I don't love him, I just think your argument is absurd and feel obliged to reply since I know something about his content (unlike yourself). I do realize it's a complete waste of my time discussing this with you, because you saw a tweet you didn't like and therefore nothing he said in the past or ever says in the future is relevant.

I can see you will only consider covid takes from medical people if you agree with the content. There's nothing wrong with this type of bias, in fact everybody is biased in some way so it's all good. Just tell me what I want to hear!!
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Almost! I don't have opinions! I do like to follow the consensus of qualified experts as opposed to free thinkers who do their own research and have contrarian opinions. Attia may not even be that. I don't know him. I'm only commenting on his grifting. This has nothing to do with the tweet or anything he said about covid (I listened to one podcast that, while inaccurate in many parts based on the actual data, wasn't that bad).

Nothing I have said about his grifting is not based on facts. Which is fine. He has the right to do that. He's not alone! Freedom!
 
Preston said:
Almost! I don't have opinions! I do like to follow the consensus of qualified experts as opposed to free thinkers who do their own research and have contrarian opinions. Attia may not even be that. I don't know him. I'm only commenting on his grifting. This has nothing to do with the tweet or anything he said about covid (I listened to one podcast that, while inaccurate in many parts based on the actual data, wasn't that bad).

Nothing I have said about his grifting is not based on facts. Which is fine. He has the right to do that. He's not alone! Freedom!
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A person who can't tell the difference between Peter Attia and Dr. Oz cannot be counted on to evaluate either one.

But then again, everything Kristian Andersen and Neil Young have to say on medical issues should be believed because they're both on our team!!

P.S. Cancel all people who do things for money!
 
axlsalinger said:
A person who can't tell the difference between Peter Attia and Dr. Oz cannot be counted on to evaluate either one.

But then again, everything Kristian Andersen and Neil Young have to say on medical issues should be believed because they're both on our team!!

P.S. Cancel all people who do things for money!
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Sir, I don't get medical information from Neil Young. I do get it from one of the top virologists on the planet though, agreed. I don't want Attia canceled. I have complimented him aggressively throughout. He is remarkably talented and made a fairly large career for himself in media. That is not easy to do. He has charisma and is a great communicator.

But he does treat patients based on a science in its infancy with minimal data to support any potential treatment. By definition, that's grifting. All of this is factual. I'm not mad and I don't think he should be canceled or stopped. You keep implying that I am which is weird. I'm simply stating facts and you're responding with how you think I feel. None of what I've said is an opinion.
 
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These people are both clowns. We know this because one has been acting and talking like a clown for 20 years, and the other one posted a tweet that I disagree with! Why do you keep saying I'm mocking the 2nd guy? I said he's probably very nice and charismatic!
 
Is he your dad or something? This is very strange. I can't relate to this level of idolization between Rogan and now with this guy. It's ok to admit things about him and still listen to his podcast if it's entertaining. Who cares? All of these guys have baggage. Some just happen to be qualified and practice an accredited form of medicine. Others don't. And there are plenty of morons who actually practice real medicine so if you keep thinking this is a knock on him personally, I can assure you it isn't.
 
Did he kick your dog or something? This is very strange. I can't relate to this level of hatred between Rogan and now with this guy. It's ok to admit good things about him and still not listen to his podcast if you don't find it entertaining. Who cares? All of these guys have baggage. I suppose it makes it easier to conclude every single doctor you disagree with is a quack if you mock each one as not being worth engaging in a discussion about facts and data.
 
I'll say it again. I don't disagree with anything he has said because I don't read his stuff. If he is anti vaccine mandate I probably even lean on his side at this point. I haven't commented on any of his opinions. He tweeted a stupid thing obviously but that was it.

1. No completed residency
2. Not board certified
3. Doesn't practice in an actual existing field of medicine with actual translational research.

Typically research and medical breakthroughs with proven treatments come before practice, but in this case he's treating patients based on incomplete data. That's a grift. We would say the same about those naturopathic doctor wackjobs. Until concrete evidence exists and until the science and field is recognized as an accredited form of medicine he is treating patients based on pseudoscience. That's the all I've said. All truth, none made up. It's okay to say "yeah he is grifting people at this point but there is a lot of promise in some of this stuff and maybe some of it will make a big difference." That's fine. You're taking this way too personally, unless you're related to him. In that case, I get it.
 
It's ridiculous to write off his practice because you know absolutely nothing about it.

I always questioned chiropractors because it seems like pseudoscience, but I had back pain once and since it was covered by my workplace saw a chiropractor for a while. Ended up enjoying the sessions and got rid of the back pain. I'm still a little skeptical but I can't dismiss it because I just don't know enough about it. A lot of people swear it works and it helped me too. Same goes for acupuncture.

I'm pretty sure none of the "holistic" fraud types or even chiropractors spent 7 years at Johns Hopkins and the NIH. If you were to listen to him for a few hours with an open mind, I suspect you would say he is a smart and data-driven guy. But maybe not!

I made my case and will now let you have the last word, so work on a nice passive-aggressive insult that sounds like a compliment and make it count!
 
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axlsalinger said:
It's ridiculous to write off his practice because you know absolutely nothing about it.

I always questioned chiropractors because it seems like pseudoscience, but I had back pain once and since it was covered by my workplace saw a chiropractor for a while. Ended up enjoying the sessions and got rid of the back pain. I'm still a little skeptical but I can't dismiss it because I just don't know enough about it. A lot of people swear it works and it helped me too. Same goes for acupuncture.

I'm pretty sure none of the "holistic" fraud types or even chiropractors spent 7 years at Johns Hopkins and the NIH. If you were to listen to him for a few hours with an open mind, I suspect you would say he is a smart and data-driven guy.

I made my case and will now let you have the last word, so work on a nice passive-aggressive insult that sounds like a compliment and make it count!
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I'm not writing it off. You keep inserting opinions into my posts which have thus far only dealt with facts. I'm just calling the treating of people with treatments based on incomplete/insufficient data for what it is. That's all. Didn't make a single comment on his intelligence or his covid opinions or anything. The closest I came was calling his one tweet horrible (which happens to the best of them!).

Anyway I love you and I'm glad we had a beautiful civil conversation.
 


Tldr: more data showing that omicron likely came from a chronic infection from an HIV fella. The solution? Vaccinate the world, antivirals to the immunocompromised.

What would that do? Likely give us a more predictable set of mutations, giving us a much easier time to match vaccines (assuming ones with broader coverage don't ever come).

https://yourlocalepidemiologist.substack.com/p/predicting-the-next-booster?justPublished=true

CoV-229E is probably a good indicator of what’s to come with SARS-CoV-2 because the viruses look fairly similar. Also, and importantly, they are mutating largely in the same physical places. The purpose of this study was to assess how CoV-229E evolved over time, which may give us some insight into how SARS-CoV-2 will mutate over time. So what did they find?

CoV-229E mutated over time in a clear ladder-like pattern, just like the flu (see figure below).

Over time, mutations of CoV-229E eroded antibody protection. In other words, people that were only infected by CoV-229E in 1984 weren’t well protected today.

The rate of antibody erosion was highly variable across people.
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This tells us that we should expect a ladder-like evolution of SARS-CoV-2 through which we could predict the next variant.

However, much to our surprise, this hasn’t happened

SARS-CoV-2 has thrown us for a loop, as the mutations haven’t evolved in a ladder-like fashion.
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But (and this is a big but), we haven’t had a lot of time for this pattern to play out. It’s only been 2 years and other evolutionary trees, like CoV-229E, also had 2-year time frames in which there were no ladder-like changes.

We expect the ladder-like pattern to arise with SARS-CoV-2 eventually. But because it hasn’t yet, we don’t know which direction SARS-CoV-2 is heading
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