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OT: Coronavirus Resources - and other things to not worry about



Original antigenic sin is a real problem that we may have to deal with. It exists with the flu. Basically your immune system is imprinted with the first exposure you have to a pathogen, whether it's through vax or infection. So basically you keep making immune responses aimed at the og strain or variant even when you're exposed to different strains/variants later in life. This doesn't ENTIRELY prevent new primary responses against OTHER parts but it's possible those responses get slowed or are weaker. So for example, for HL, she would probably kick the shit out of Alpha-like variants better than us. Or at least her immune system would recognize it better than us and work faster to fight it.

I recall reading something a while back that during one of the flu pandemics the older folks did quite well and the younger folks did poorly. This was because the flu was quite similar to one of the flu strains that many old folks were exposed to very early in their life. So through Original Antigenic Sin, they were able to fight it off far better than young folks. It's kinda interesting and can work as a blessing too sometimes. It's luck of the draw largely, though it may limit true robust broad-level protection in some regard.
 
Haven't heard this before... Btw Rogan's theory/argument here has been debunked since this video. He has always been like this. Timestamped video:

 
And yeah, he's such an asshole that during the peak of Howard Stern's douchery, him and his staff members were appalled at his verbal harassment of strippers when they did their show in Vegas for a week in the early 2000s. But his popularity doesn't have anything to do with him being a nice guy of course.
 
Preston said:
Haven't heard this before... Btw Rogan's theory/argument here has been debunked since this video. He has always been like this. Timestamped video:

Click to expand...



This is the guy in a nutshell, pretty much.

This lady’s PHD in the topic at hand < Rogan’s “research” online.
 
Preston said:


Original antigenic sin is a real problem that we may have to deal with. It exists with the flu. Basically your immune system is imprinted with the first exposure you have to a pathogen, whether it's through vax or infection. So basically you keep making immune responses aimed at the og strain or variant even when you're exposed to different strains/variants later in life. This doesn't ENTIRELY prevent new primary responses against OTHER parts but it's possible those responses get slowed or are weaker. So for example, for HL, she would probably kick the shit out of Alpha-like variants better than us. Or at least her immune system would recognize it better than us and work faster to fight it.

I recall reading something a while back that during one of the flu pandemics the older folks did quite well and the younger folks did poorly. This was because the flu was quite similar to one of the flu strains that many old folks were exposed to very early in their life. So through Original Antigenic Sin, they were able to fight it off far better than young folks. It's kinda interesting and can work as a blessing too sometimes. It's luck of the draw largely, though it may limit true robust broad-level protection in some regard.
Click to expand...


Yeah, I think that was the 1970s influenza outbreak. Anyone who was around in 1919 still kept some immunities to that, so that new outbreak had a bigger impact on the younger generation than the old folks.
 
Preston said:
And yeah, he's such an asshole that during the peak of Howard Stern's douchery, him and his staff members were appalled at his verbal harassment of strippers when they did their show in Vegas for a week in the early 2000s. But his popularity doesn't have anything to do with him being a nice guy of course.
Click to expand...
He's a man's man!
 
Preston said:
Haven't heard this before... Btw Rogan's theory/argument here has been debunked since this video. He has always been like this. Timestamped video:

Click to expand...

wow what an epic jackass. when is this from? this makes me think I was being charitable in my previous assessment of his video.

what a fucking jackass.
 
Wayward DP said:
wow what an epic jackass. when is this from? this makes me think I was being charitable in my previous assessment of his video.

what a fucking jackass.
Click to expand...
2005 on the Opie and Anthony show. I think he has calmed down since his podcast.

TLDR: Rogan will listen to anyone who excites his limbic system. He is especially fond of speaking to people who make him think of himself as an extra-informed iconoclast who "questions the narrative" and "entertains outsider ideas". In reality, Rogan is a profoundly ignorant stoner with an extremely mediocre mind who has somehow created a following by saying "wowww mannnn, that's so cooooollll" to any lamebrained idea that crops up on his show.
 
Preston said:
2005 on the Opie and Anthony show. I think he has calmed down since his podcast.

TLDR: Rogan will listen to anyone who excites his limbic system. He is especially fond of speaking to people who make him think of himself as an extra-informed iconoclast who "questions the narrative" and "entertains outsider ideas". In reality, Rogan is a profoundly ignorant stoner with an extremely mediocre mind who has somehow created a following by saying "wowww mannnn, that's so cooooollll" to any lamebrained idea that crops up on his show.
Click to expand...
Lol

so much for the you’re phd from 2000 is dated argument
 
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