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OT: Health and Nutrition

Your online friend’s statement — “obesity is largely a mental health disease” — captures one important piece of the puzzle, but most researchers would say it’s too narrow to describe the whole condition. Obesity is generally understood as a multifactorial chronic disease involving biology, environment, behavior, and sometimes mental health.
 
zeke said:
Does it just remove dopamine rewards for everything, including good things?
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It doesn't remove dopamine rewards, just regulates them.

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www.uab.edu

The GLP-1 revolution: What UAB researchers are discovering about how these drugs work

GLP‑1 weight‑loss drugs like semaglutide and tirzepatide are redefining how scientists and the public understand obesity, appetite and metabolic disease. At the University of Alabama at Birmingham, researchers are uncovering how these medications work in the brain.
www.uab.edu www.uab.edu
 
just a result of a sedentary culture with overwhelming access to plentiful processed food and a constant barrage of advertising and other triggers imo.
 
MindzEye said:
It doesn't remove dopamine rewards, just regulates them.

View attachment 33041

www.uab.edu

The GLP-1 revolution: What UAB researchers are discovering about how these drugs work

GLP‑1 weight‑loss drugs like semaglutide and tirzepatide are redefining how scientists and the public understand obesity, appetite and metabolic disease. At the University of Alabama at Birmingham, researchers are uncovering how these medications work in the brain.
www.uab.edu www.uab.edu
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59iWeRy.gif
 
zeke said:
1. The ghastly empty look of people who take it
2. Just basic skepticism that something that seems to have such a strong effect on so many things would end up only being positive effects.
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Does seem too good to he true but what out there doesn't have major short term side effects but massive long term effects?
 
CH1 said:
Your online friend’s statement — “obesity is largely a mental health disease” — captures one important piece of the puzzle, but most researchers would say it’s too narrow to describe the whole condition. Obesity is generally understood as a multifactorial chronic disease involving biology, environment, behavior, and sometimes mental health.
Click to expand...
Woke ass AI!

But yeah, Zeke, it's definitely being abused by many. And there are risks and things you need to do while you're on it like eat healthy. You're eating less so it becomes even more important to get your nutrients and eat healthy and don't skip meals and risk being malnourished and stuff.

Is it better to go to the gym, go to therapy to reduce the food noise, and get on a strict diet by raw digging it? Yeah obviously. But that isn't happening and will never happen. Food addiction is real, drug addiction is real and now there's a drug that can possibly treat both. Kind of exciting.
 
zeke said:
59iWeRy.gif
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Not at all.

Remove is bad. This is how you no longer take pleasure in basically anything. Regulate is good, this is how things that you've conditioned yourself to rely on the dopamine hit of for your overall mental well being (social media likes, prop bets, and yes delicious greezy food), become less (but not, not) appealing to you.
 
so you're saying that the dopamine hit can only be blunted so much, or that the drug companies make sure to blunt it only so much, or that the dosage determines how much it's blunted?
 
MindzEye said:
Not at all.

Remove is bad. This is how you no longer take pleasure in basically anything. Regulate is good, this is how things that you've conditioned yourself to rely on the dopamine hit of for your overall mental well being (social media likes, prop bets, and yes delicious greezy food), become less (but not, not) appealing to you.
Click to expand...
As with anything, people react differently to the drugs. Some people anecdotally do experience some form of anhedonia. Not everyone and clearly the vast minority. And this doesn't mean they experience no pleasure in everything, just reduced pleasure. But for most people, it's only proven to have that impact with food and now most likely alcohol too.

But again I say, adhedonia vs obesity. Which is gonna reduce your life expectancy? I'd take that tradeoff.
 
zeke said:
so you're saying that the dopamine hit can only be blunted so much, or that the drug companies make sure to blunt it only so much, or that the dosage determines how much it's blunted?
Click to expand...

I'm saying that the way dopamine works isn't just an on/off switch on this one type of receptor and the mechanism of these drugs doesn't just turn off the receptors. It's complicated, and the end result of using the drug is that you're no long hyper stimulated by your previous dopamine addictions while on it.
 
Like at the end of the day the goal is to treat food addiction for most. And it accomplishes that at crazy, historic levels. Many of these people were suffering and their quality of life even beyond just the weight has improved substantially. They are no longer controlled by food. That is incredibly freeing just from a mental health perspective.
 
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