It's hard to compare players draft over draft and even league over league.
However, what is definitely possible is to compare them in best on best tournaments at the same points in their careers.
Lafrenière, Bedard, Carlsson, Fantilli and Dvorsky are all in the U20 WJC during their first draft season. Since they all play(ed) in different leagues (QMJHL, WHL, NCAA, SEL, & Sweden second tier) there's no direct comparisons, which only leaves us the WJC. If Russia wasn't doing Russia things, Michkov would be part of the discussion as well, alas...
So, let's compare what they did / are doing in the WJC.
Bedard: All time performance, can't say a bad thing about him.
Lafrenière: Dominant at 18 years old, named tournament MVP.
Carlsson: Playing well, holding his own, but he's not a dominant force.
Fantilli: Underwhelming.
Dvorsky: Haven't really paid attention to him.
Based on only their WJC performances, Bedard is grossly superior to everyone, and Lafrenière was much better than everyone else.
I don't know what's going on with Lafrenière in New York, but his production in the NHL so far hasn't been great. I would 100% take a chance on him without even blinking.